TRI77

Details:

UniProt Entry: I1YAP6
Gene: TRIM77
Class: RING
Family: RING5
Protein length: 450
Database confidence: 0.625
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link

Protein Sequence ▾

>I1YAP6
MASAITQCST SELTCSICTD YLTDPVTICC GHRFCSPCLC LLWEDTLTPN CCPVCREISQ
QMYFKRIIFA EKQVIPTRES VPCQLSSSAM LICRRHQEIK NLICETDRSL LCFLCSQSPR
HATHKHYMTR EADEYYRKKL LIQMKSIWKK KQKNQRNLNR ETNIIGTWEV FINLRSMMIS
AEYPKVCQYL REEEQKHVES LAREGRIIFQ QLKRSQTRMA KMGILLREMY EKLKEMSCKA
DVNLPQDLGD VMKRNEFLRL AMPQPVNPQL SAWTITGVSE RLNFFRVYIT LDRKICSNHK
LLFEDLRHLQ CSLDDTDMSC NPTSTQYTSS WGAQILSSGK HYWEVDVKDS CNWVIGLCRE
AWTKRNDMRL DSEGIFLLLC LKVDDHFSLF STSPLLPHYI PRPQGWLGVF LDYECGIVSF
VNVAQSSLIC SFLSRIFYFP LRPFICHGSK

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
2	80	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
15	55	Domain	Zinc finger, C3HC4 RING-type	IPR018957	PF00097
15	56	Domain	Zinc finger, RING-type	IPR001841	PS50089
15	55	Domain	Zinc finger, RING-type	IPR001841	SM00184
30	39	Conserved_site	Zinc finger, RING-type, conserved site	IPR017907	PS00518
88	129	Domain	B-box-type zinc finger	IPR000315	SM00336
88	131	Domain	B-box-type zinc finger	IPR000315	PS50119
269	450	Domain	B30.2/SPRY domain	IPR001870	PS50188
280	448	Homologous_superfamily	Concanavalin A-like lectin/glucanase domain superfamily	IPR013320	SSF49899
281	450	Homologous_superfamily	B30.2/SPRY domain superfamily	IPR043136	G3DSA:2.60.120.920
285	302	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
323	347	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
340	448	Domain	SPRY domain	IPR003877	PF00622
353	366	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
398	422	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
429	447	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0010468	regulation of gene expression	Biological Process	IBA	GO_REF:0000033
GO:0045087	innate immune response	Biological Process	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IBA	GO_REF:0000033
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IBA	GO_REF:0000033

Enzyme–Substrate Interactions ▾

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