RN223

Details:

UniProt Entry: E7ERA6
Gene: RNF223
Class: RING
Family: RING4
Protein length: 249
Database confidence: 0.125
InterPro: InterPro Entry
Mode of Action: Unclassified
AlphaFold Model: Link

Protein Sequence ▾

>E7ERA6
MSSGQQVWHT AVPPPRRSSS IASMPRSPSS AGSPRSPGTP GSERVASPLE CSICFSGYDN
IFKTPKELSC THVFCLECLA RLAAAQPVGR PGGEAVPCPF CRQPTAVPPA GAPALCTSRQ
LQARMPAHLR REEPVWLEGT KLCCQPLPTT PGREPGFVCV DVGLSKPAEP PAPARDPAPR
RGRLARCWAR CRDWRRMALV SALLLMLFCV ALWPVQCALK TGNLRCLPLP PRPPATSTAA
SPLGPLTDN

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
41	131	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
50	102	Domain	Zinc finger, RING-type	IPR001841	PF13639
51	101	Domain	Zinc finger, RING-type	IPR001841	SM00184
51	102	Domain	Zinc finger, RING-type	IPR001841	PS50089
70	79	Conserved_site	Zinc finger, RING-type, conserved site	IPR017907	PS00518

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0016567	protein ubiquitination	Biological Process	IBA	GO_REF:0000033
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000120
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IBA	GO_REF:0000033

Enzyme–Substrate Interactions ▾

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