KBTBD

Details:

UniProt Entry: C9JR72
Gene: KBTBD13
Class: Other E3 Components
Family: Adaptor
Protein length: 458
Database confidence: 0.25
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>C9JR72
MARGPQTLVQ VWVGGQLFQA DRALLVEHCG FFRGLFRSGM RETRAAEVRL GVLSAGGFRA
TLQVLRGDRP ALAAEDELLQ AVECAAFLQA PALARFLEHN LTSDNCALLC DAAAAFGLRD
VFHSAALFIC DGERELAAEL ALPEARAYVA ALRPSSYAAV STHTPAPGFL EDASRTLCYL
DEEEDAWRTL AALPLEASTL LAGVATLGNK LYIVGGVRGA SKEVVELGFC YDPDGGTWHE
FPSPHQPRYD TALAGFDGRL YAIGGEFQRT PISSVERYDP AAGCWSFVAD LPQPAAGVPC
AQACGRLFVC LWRPADTTAV VEYAVRTDAW LPVAELRRPQ SYGHCMVAHR DSLYVVRNGP
SDDFLHCAID CLNLATGQWT ALPGQFVNSK GALFTAVVRG DTVYTVNRMF TLLYAIEGGT
WRLLREKAGF PRPGSLQTFL LRLPPGAPGP VTSTTAEL

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
7	137	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
7	74	Domain	BTB/POZ domain	IPR000210	PS50097
9	102	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
9	103	Domain	BTB/POZ domain	IPR000210	PF00651
166	430	Homologous_superfamily	Kelch-type beta propeller	IPR015915	G3DSA:2.120.10.80
168	425	Homologous_superfamily	Kelch-type beta propeller	IPR015915	SSF117281
201	244	Repeat	Kelch repeat type 1	IPR006652	PF01344
210	258	Repeat	Kelch repeat type 1	IPR006652	SM00612
247	292	Repeat	Kelch repeat type 1	IPR006652	PF01344
259	305	Repeat	Kelch repeat type 1	IPR006652	SM00612

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0007015	actin filament organization	Biological Process	IEA	GO_REF:0000107
GO:0014728	regulation of the force of skeletal muscle contraction	Biological Process	IEA	GO_REF:0000107
GO:0090076	relaxation of skeletal muscle	Biological Process	IEA	GO_REF:0000107
GO:0016567	protein ubiquitination	Biological Process	IEA	GO_REF:0000041
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000120
GO:0005829	cytosol	Cellular Component	TAS	Reactome:R-HSA-8952630
GO:0005515	protein binding	Molecular Function	IPI	PMID:22542517
GO:0051015	actin filament binding	Molecular Function	IEA	GO_REF:0000107

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