BTBDI

Details:

UniProt Entry: B2RXH4
Gene: BTBD18
Class: Other E3 Components
Family: Adaptor
Protein length: 712
Database confidence: 0.125
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>B2RXH4
MCSPASPKIL YRNPRFLRLA FLQLHHQQQS DVFCDVLLQA EGEAVPAHCC ILSACSPFFT
ERLERERPAQ GGKVVLELGG LKISTLRKLV DFLYTSEMEV SQEEAQDVLS AARQLRVSEL
ESLQLEGGKL VKAPQGRRLN RECLQPTSAA PISARVVTPS HHPHTPLPTN QTPCPLGAIR
LKSLGKEEGP QENNRQNADN LSGTLLLKRK ARACPTPQEK NSSPSSHSQE PRENKNDTAL
DPTVLSPPSL YPSVDKHLLP RKIRLSRSKP SPGICTSKPS SILSGSSSVP ATPGRRLWRQ
RSVNKETPED KPKPGRASPL QSTPNPSGLG KTGGSRKRSP EVRAPNSDSA EEGQVGRVKL
RKIVNGTCWE VVQETPLKNT QDSPQIPDPG GDFQEPSGTQ PFSSNEQEMS PTRTELCQDS
PMCTKLQDIL VSASHSPDHP VVKSEFESSP ELVEKEPMLA IDCREPYAFD TALLEQPCEA
EEYRITSAAA TSELEEILDF MLCGSDIEPP IGSLESPGAE GCRTPTYHLT ETGKNWIEGE
EWCLPDMELW PRELTELEKE PAGENRGPTE LLSPLVMPSE VSEVLSVGGR WTPDLEITSS
QPLDGQEDKL LHVSSLDTPQ RSYGDLSPPC SNWVETGLEV SLTTDELLYP SPKAGKEVSG
HSELLGSLPA SSEEEEIDVV DWTAEGRLVP TTVPSVWPDP SSESETEVDI LT

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
1	712	Family	BTB/POZ domain-containing protein 18	IPR042915	PTHR47639
10	122	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
13	135	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
25	121	Domain	BTB/POZ domain	IPR000210	PF00651
34	102	Domain	BTB/POZ domain	IPR000210	PS50097
34	132	Domain	BTB/POZ domain	IPR000210	SM00225

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0010526	transposable element silencing	Biological Process	ISS	GO_REF:0000024
GO:0007141	male meiosis I	Biological Process	ISS	GO_REF:0000024
GO:0007283	spermatogenesis	Biological Process	ISS	GO_REF:0000024
GO:0030154	cell differentiation	Biological Process	IEA	GO_REF:0000043
GO:0032968	positive regulation of transcription elongation by RNA polymerase II	Biological Process	IEA	GO_REF:0000002
GO:0140541	piRNA transcription	Biological Process	ISS	GO_REF:0000024
GO:0005634	nucleus	Cellular Component	IBA	GO_REF:0000033
GO:0005515	protein binding	Molecular Function	IPI	PMID:32296183

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