ZBT42

Details:

UniProt Entry: B2RXF5
Gene: ZBTB42
Class: RING
Family: RING6
Protein length: 422
Database confidence: 0.125
InterPro: InterPro Entry
Mode of Action: Complex
AlphaFold Model: Link

Protein Sequence ▾

>B2RXF5
MEFPEHGGRL LGRLRQQREL GFLCDCTVLV GDARFPAHRA VLAACSVYFH LFYRDRPAGS
RDTVRLNGDI VTAPAFGRLL DFMYEGRLDL RSLPVEDVLA AASYLHMYDI VKVCKGRLQE
KDRSLDPGNP APGAEPAQPP CPWPVWTADL CPAARKAKLP PFGVKAALPP RASGPPPCQV
PEESDQALDL SLKSGPRQER VHPPCVLQTP LCSQRQPGAQ PLVKDERDSL SEQEESSSSR
SPHSPPKPPP VPAAKGLVVG LQPLPLSGEG SRELELGAGR LASEDELGPG GPLCICPLCS
KLFPSSHVLQ LHLSAHFRER DSTRARLSPD GVAPTCPLCG KTFSCTYTLK RHERTHSGEK
PYTCVQCGKS FQYSHNLSRH TVVHTREKPH ACRWCERRFT QSGDLYRHVR KFHCGLVKSL
LV

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
1	129	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
2	120	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
14	121	Domain	BTB/POZ domain	IPR000210	PF00651
24	122	Domain	BTB/POZ domain	IPR000210	SM00225
24	92	Domain	BTB/POZ domain	IPR000210	PS50097
294	316	Domain	Zinc finger C2H2-type	IPR013087	SM00355
294	321	Domain	Zinc finger C2H2-type	IPR013087	PS50157
294	316	Domain	Zinc finger C2H2-type	IPR013087	PS00028
334	356	Domain	Zinc finger C2H2-type	IPR013087	SM00355
334	361	Domain	Zinc finger C2H2-type	IPR013087	PS50157
335	364	Homologous_superfamily	Zinc finger C2H2 superfamily	IPR036236	SSF57667
336	356	Domain	Zinc finger C2H2-type	IPR013087	PS00028
356	408	Homologous_superfamily	Zinc finger C2H2 superfamily	IPR036236	SSF57667
362	384	Domain	Zinc finger C2H2-type	IPR013087	PF00096
362	384	Domain	Zinc finger C2H2-type	IPR013087	SM00355
362	389	Domain	Zinc finger C2H2-type	IPR013087	PS50157
364	384	Domain	Zinc finger C2H2-type	IPR013087	PS00028
390	413	Domain	Zinc finger C2H2-type	IPR013087	SM00355
390	418	Domain	Zinc finger C2H2-type	IPR013087	PS50157
391	413	Domain	Zinc finger C2H2-type	IPR013087	PF00096
392	413	Domain	Zinc finger C2H2-type	IPR013087	PS00028

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0000122	negative regulation of transcription by RNA polymerase II	Biological Process	IEA	GO_REF:0000107
GO:0006357	regulation of transcription by RNA polymerase II	Biological Process	IBA	GO_REF:0000033
GO:0007517	muscle organ development	Biological Process	IMP	PMID:25055871
GO:0005634	nucleus	Cellular Component	IBA	GO_REF:0000033
GO:0005654	nucleoplasm	Cellular Component	ISS	GO_REF:0000024
GO:0005737	cytoplasm	Cellular Component	IEA	GO_REF:0000120
GO:0005886	plasma membrane	Cellular Component	IDA	GO_REF:0000052
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Molecular Function	IBA	GO_REF:0000033
GO:0003677	DNA binding	Molecular Function	IEA	GO_REF:0000043
GO:0005515	protein binding	Molecular Function	IPI	PMID:32296183
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000043
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000043

Enzyme–Substrate Interactions ▾

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