ABTB3

Details:

UniProt Entry: A6QL63
Gene: ABTB3
Class: Other E3 Components
Family: Adaptor
Protein length: 1104
Database confidence: 0.25
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>A6QL63
MARRGKKPVV RTLEDLTLDS GYGGAADSVR SSNLSLCCSD SHPASPYGGS CWPPLADSMH
SRHNSFDTVN TALVEDSEGL DCAGQHCSRL LPDLDEVPWT LQELEALLLR SRDPRAGPAV
PGGLPKDALA KLSTLVSRAL VRIAKEAQRL SLRFAKCTKY EIQSAMEIVL SWGLAAHCTA
AALAALSLYN MSSAGGDRLG RGKSARCGLT FSVGRVYRWM VDSRVALRIH EHAAIYLTAC
MESLFRDIYS RVVASGVPRS CSGPGSGSGS GPGPSSGPGA APAADKEREA PGGGAASGGA
CSAASSASGG SSCCAPPAAA AAAVPPAAAA NHHHHHHHAL HEAPKFTVET LEHTVNNDSE
IWGLLQPYQH LICGKNASGV LCLPDSLNLH RDPQRSNKPG ELPMFSQSEL RTIEQSLLAT
RVGSIAELSD LVSRAMHHLQ PLNAKHHGNG TPLHHKQGAL YWEPEALYTL CYFMHCPQME
WENPNVEPSK VNLQVERPFL VLPPLMEWIR VAVAHAGHRR SFSMDSDDVR QAARLLLPGV
DCEPRQLRAD DCFCASRKLD AVAIEAKFKQ DLGFRMLNCG RTDLVKQAVS LLGPDGINTM
SEQGMTPLMY ACVRGDEAMV QMLLDAGADL NVEVVSTPHK YPSVHPETRH WTALTFAVLH
GHIPVVQLLL DAGAKVEGSV EHGEENYSET PLQLAAAVGN FELVSLLLER GADPLIGTMY
RNGISTTPQG DMNSFSQAAA HGHRNVFRKL LAQPEKEKSD ILSLEEILAE GTDLAETAPP
PLCASRNSKA KLRALREAMY HSAEHGYVDV TIDIRSIGVP WTLHTWLESL RIAFQQHRRP
LIQCLLKEFK TIQEEEYTEE LVTQGLPLMF EILKASKNEV ISQQLCVIFT HCYGPYPIPK
LTEIKRKQTS RLDPHFLNNK EMSDVTFLVE GRPFYAHKVL LFTASPRFKA LLSSKPTNDG
TCIEIGYVKY SIFQLVMQYL YYGGPESLLI KNNEIMELLS AAKFFQLEAL QRHCEIICAK
SINTDNCVDI YNHAKFLGVT ELSAYCEGYF LKNMMVLIEN EAFKQLLYDK NGEGTGQDVL
QDLQRTLAIR IQSIHLSSSK GSVV

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
115	255	Homologous_superfamily	Histone-fold	IPR009072	G3DSA:1.10.20.10
123	191	Homologous_superfamily	Histone-fold	IPR009072	SSF47113
201	389	Homologous_superfamily	Histone-fold	IPR009072	SSF47113
564	865	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	G3DSA:1.25.40.20
578	752	Homologous_superfamily	Ankyrin repeat-containing domain superfamily	IPR036770	SSF48403
603	632	Repeat	Ankyrin repeat	IPR002110	SM00248
603	635	Repeat	Ankyrin repeat	IPR002110	PS50088
604	631	Repeat	Ankyrin repeat	IPR002110	PF00023
649	714	Repeat	Ankyrin repeat	IPR002110	PF12796
649	678	Repeat	Ankyrin repeat	IPR002110	SM00248
649	681	Repeat	Ankyrin repeat	IPR002110	PS50088
687	716	Repeat	Ankyrin repeat	IPR002110	SM00248
687	713	Repeat	Ankyrin repeat	IPR002110	PS50088
730	760	Repeat	Ankyrin repeat	IPR002110	SM00248
901	1051	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
914	1021	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
916	1020	Domain	BTB/POZ domain	IPR000210	PF00651
923	1022	Domain	BTB/POZ domain	IPR000210	SM00225
923	983	Domain	BTB/POZ domain	IPR000210	PS50097

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0035249	synaptic transmission, glutamatergic	Biological Process	IEA	GO_REF:0000107
GO:0035640	exploration behavior	Biological Process	IEA	GO_REF:0000107
GO:0050821	protein stabilization	Biological Process	IEA	GO_REF:0000107
GO:0016020	membrane	Cellular Component	IEA	GO_REF:0000120
GO:0098978	glutamatergic synapse	Cellular Component	IEA	GO_REF:0000107
GO:0030165	PDZ domain binding	Molecular Function	IEA	GO_REF:0000107
GO:0046982	protein heterodimerization activity	Molecular Function	IEA	GO_REF:0000002

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