TRI64

Details:

UniProt Entry: A6NGJ6
Gene: TRIM64
Class: RING
Family: RING5
Protein length: 449
Database confidence: 0.5
InterPro: InterPro Entry
Mode of Action: Standalone
AlphaFold Model: Link

Protein Sequence ▾

>A6NGJ6
MDSDDLQVFQ NELICCICVN YFIDPVTIDC GHSFCRPCLC LCSEEGRAPM RCPSCRKISE
KPNFNTNVVL KKLSSLARQT RPQNINSSDN ICVLHEETKE LFCEADKRLL CGPCSESPEH
MAHSHSPIGW AAEECREKLI KEMDYLWEIN QETRNNLNQE TRTFHSLKDY VSVRKRIITI
QYQKMPIFLD EEEQRHLQAL EREAEELFQQ LQDSQVRMTQ HLERMKDMYR ELWETCHVPD
VELLQDVRNV SARTDLAQMQ KPQPVNPELT SWCITGVLDM LNNFRVDSAL STEMIPCYIS
LSEDVRYVIF GDDHLSAPTD PQGVDSFAVW GAQAFTSGKH YWEVDVTLSS NWILGVCQDS
RTADANFVID SDERFFLISS KRSNHYSLST NSPPLIQYVQ RPLGQVGVFL DYDNGSVSFF
DVSKGSLIYG FPPSSFSSPL RPFFCFGCT

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
2	77	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	IPR013083	G3DSA:3.30.40.10
15	55	Domain	Zinc finger, RING-type	IPR001841	SM00184
15	56	Domain	Zinc finger, RING-type	IPR001841	PS50089
15	55	Domain	Zinc finger, C3HC4 RING-type	IPR018957	PF00097
30	39	Conserved_site	Zinc finger, RING-type, conserved site	IPR017907	PS00518
87	128	Domain	B-box-type zinc finger	IPR000315	SM00336
87	128	Domain	B-box-type zinc finger	IPR000315	PS50119
268	449	Domain	B30.2/SPRY domain	IPR001870	PS50188
277	449	Homologous_superfamily	B30.2/SPRY domain superfamily	IPR043136	G3DSA:2.60.120.920
278	448	Homologous_superfamily	Concanavalin A-like lectin/glucanase domain superfamily	IPR013320	SSF49899
301	318	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
337	449	Domain	SPRY domain	IPR003877	SM00449
339	447	Domain	SPRY domain	IPR003877	PF00622
352	365	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
397	421	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407
428	446	Domain	Butyrophylin-like, SPRY domain	IPR003879	PR01407

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0010468	regulation of gene expression	Biological Process	IBA	GO_REF:0000033
GO:0045087	innate immune response	Biological Process	IBA	GO_REF:0000033
GO:0005737	cytoplasm	Cellular Component	IBA	GO_REF:0000033
GO:0008270	zinc ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0046872	metal ion binding	Molecular Function	IEA	GO_REF:0000120
GO:0061630	ubiquitin protein ligase activity	Molecular Function	IBA	GO_REF:0000033

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