BTBDH

Details:

UniProt Entry: A6NE02
Gene: BTBD17
Class: Other E3 Components
Family: Adaptor
Protein length: 478
Database confidence: 0.125
InterPro: InterPro Entry
Mode of Action: unknown
AlphaFold Model: Link

Protein Sequence ▾

>A6NE02
MPRRGYSKPG SWGSFWAMLT LVGLVTHAAQ RADVGGEAAG TSINHSQAVL QRLQELLRQG
NASDVVLRVQ AAGTDEVRVF HAHRLLLGLH SELFLELLSN QSEAVLQEPQ DCAAVFDKFI
RYLYCGELTV LLTQAIPLHR LATKYGVSSL QRGVADYMRA HLAGGAGPAV GWYHYAVGTG
DEALRESCLQ FLAWNLSAVA ASTEWGAVSP ELLWQLLQRS DLVLQDELEL FHALEAWLGR
ARPPPAVAER ALRAIRYPMI PPAQLFQLQA RSAALARHGP AVADLLLQAY QFHAASPLHY
AKFFDVNGSA FLPRNYLAPA WGAPWVINNP ARDDRSTSFQ TQLGPSGHDA GRRVTWNVLF
SPRWLPVSLR PVYADAAGTA LPAARPEDGR PRLVVTPASS GGDAAGVSFQ KTVLVGARQQ
GRLLVRHAYS FHQSSEEAGD FLAHADLQRR NSEYLVENAL HLHLIVKPVY HTLIRTPK

Domain Architecture (From InterPro) ▾

Start	End	Type	Name	InterPro	Source
36	191	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	G3DSA:3.30.710.10
44	161	Homologous_superfamily	SKP1/BTB/POZ domain superfamily	IPR011333	SSF54695
53	159	Domain	BTB/POZ domain	IPR000210	PF00651
63	132	Domain	BTB/POZ domain	IPR000210	PS50097
63	162	Domain	BTB/POZ domain	IPR000210	SM00225
169	269	Domain	BTB/Kelch-associated	IPR011705	SM00875
170	268	Domain	BTB/Kelch-associated	IPR011705	PF07707

Protein functions ▾

GO term	Name	Ontology	Evidence	Reference
GO:0009615	response to virus	Biological Process	ISS	GO_REF:0000024
GO:0045071	negative regulation of viral genome replication	Biological Process	ISS	GO_REF:0000024
GO:0005737	cytoplasm	Cellular Component	ISS	GO_REF:0000024
GO:0005576	extracellular region	Cellular Component	IEA	GO_REF:0000120
GO:0005886	plasma membrane	Cellular Component	ISS	GO_REF:0000024

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